One of the most influential architecture firms in the nation at that time, Cope & Stewardson completed work on the Georgian Colonial Revival-style mansion during 1896 and 1897.

She subsequently named her new residence "Anoatok" in honor of the Arctic explorations of her late brother-in-law, Elisha Kent Kane.

[3] Following Elizabeth Kane's death at the mansion in 1909, ownership of the residence was awarded to her sons Evan and Thomas, the latter of whom moved out after a new home was completed for him in 1910 by Cope & Stewardson.

According to Richard F. Bly, president of Commonwealth Historic Properties, Inc. and the individual who prepared the nomination form on August 19, 1985, to secure placement of this property on the National Register of Historic Places, Anoatok was "the most prominent residence in Kane" during the 1980s, due as much to its design and craftsmanship, as to its placement on land which was 2,040 feet above sea level.

"The two parallel railings of turned wood balusters [were] painted white and [ran] between two solid buff brick cupolas."