António Teixeira de Sousa, 2nd Count of Sousa Palmela (European Portuguese pronunciation: [ɐ̃ˈtɔniu tɐjˈʃɐjɾɐ ðɨ ˈsozɐ]; 5 May 1857 – 5 June 1917) was a Portuguese medical doctor and politician during the Constitutional Monarchy.

A member of the conservative Regenerator Party, he was first elected to the Chamber of Deputies, in 1889.

He became President of the Council of Ministers (Prime Minister) on 26 June 1910, and would be the last Prime Minister of the Constitutional Monarchy as King D. Manuel II was overthrown by a republican revolution on 5 October 1910.

He left politics after the republic proclamation, but showed a moderate support for the new regime.

This article about a Portuguese politician is a stub.