Hargrove also played for the Buffalo Bills as well as winning Super Bowl XLIV with the New Orleans Saints, beating Peyton Manning and the Indianapolis Colts.
[2] Hargrove was traded by the Rams to the Buffalo Bills on October 16, 2006, in exchange for a fifth-round pick in the 2007 NFL draft.
In 2007, he played 12 games and made 28 tackles (18 solo) and had 1.5 sacks after serving a four-game suspension, which cost him $200,000 of his 2007 salary.
Due to past violations of the NFL's substance abuse policy, Hargrove received a one-year suspension on January 24, 2008.
On December 18, 2011, during a game against the Chicago Bears, wide receiver Johnny Knox sustained a serious back injury after attempting to recover his own fumble and clashing with Hargrove.
[13] On May 2, 2012, the NFL suspended Hargrove for the first eight games of the 2012 season after naming him as one of the ringleaders of the New Orleans Saints bounty scandal.
According to the league, Hargrove signed a statement admitting his role in the scheme, and also told at least one other player that the Saints had put a bounty on Brett Favre in the 2009 NFC Championship Game.
[17] On October 9, 2012, four weeks and three days after an internal appeals panel vacated suspensions imposed on Hargrove, Saints linebacker Jonathan Vilma, Browns linebacker Scott Fujita and Saints defensive end Will Smith, the league has re-issued the discipline without any changes or reductions, according to a league source.
[18] On December 12, 2012, "In a sharp rebuke to his successor's handling of the NFL's bounty investigation, former commissioner Paul Tagliabue overturned the suspensions of four current and former New Orleans Saints players (including Hargrove) in a case that has preoccupied the league for almost a year.
[21] In view of his comeback, Hargrove's Saints teammates voted him the winner of their 2009 Ed Block Courage Award.
[24] Hargrove has recently joined the MTV Mavericks Special Olympics team as the Speed and Agility trainer.
[26][27] In the spring of 2022, Hargrove was named the defensive line coach at Limestone University in Gaffney, SC, where he is a part of former NFL veteran Mike Furrey's staff.