He received a nomination for the Primetime Emmy Award for Outstanding Actor in a Supporting Role in a Limited Series or Movie for his performance in the 2020 stage recording of the play.

[4] Ramos lived in Hope Gardens Apartments, an affordable housing complex in Bushwick, Brooklyn with his mother, older brother, and younger sister.

In 2014, he performed in Heart and Lights at Radio City Music Hall, a dance show with the Rockettes which was canceled during previews.

[5] After being cast in Hamilton, Ramos played Justin Laboy in Lin-Manuel Miranda's short musical 21 Chump Street, a 14-minute, one-time performance on June 7, 2014, which was recorded for This American Life.

[10] In September 2016, it was announced that Ramos had been cast in director Spike Lee's Netflix comedy-drama series She's Gotta Have It, in the role of Mars Blackmon.

[12] In 2018, Variety reported that Ramos had been cast as Usnavi de la Vega in the film adaptation of In the Heights.

[15] In February 2022, Ramos was cast as Parker Robbins / The Hood in the upcoming superhero streaming series Ironheart, set in the Marvel Cinematic Universe.

[20] In addition to the previously released singles, the EP included two new songs, "When The Bell Tolls" and "PRayer" [sic].

He confirmed their relationship in February 2015, and on Christmas Eve 2018, he proposed to Jones in front of her favorite castle in Arundel, England.

In February 2024, Ramos' family was featured on episode 104 ("Mean Streets") of the PBS television show Finding Your Roots, a program about genealogy.