As a junior, he suffered a torn anterior cruciate ligament in his right knee against the University of Tennessee, missing the final two games of the season.

When starter Quincy Carter injured his throwing thumb, Wright became his replacement and started on September 23 against the San Diego Chargers, but had two costly turnovers in a 21–32 loss.

[8] The next week he started on Monday Night Football and contributed to a 9–7 win against Tony Banks and the Washington Redskins.

The Cowboys would use a combination of Clint Stoerner and Ryan Leaf as the starters until Carter recovered from a torn hamstring, starting a franchise-high four quarterbacks in a season.

After first round draft choice Kyle Boller injured his thigh in a game against the St. Louis Rams, Wright was activated from the practice squad on October 15.

[12] After the Ravens lost to the Miami Dolphins in his first start 6–9, Wright led a spectacular comeback against the Seahawks; with the score tied at three in the final minute of the first half, the Seahawks scored two quick touchdowns, and stormed to a 41–24 lead with seven minutes remaining, but Wright erupted with four touchdown throws and 319 passing yards in a 44–41 overtime triumph.

Ravens head coach Brian Billick gave the game ball to Wright's wife, for waiting until after the contest to induce labor.

On April 13, 2007, he signed as a free agent with the New York Giants, throwing him into a four-quarterback scramble for roster spots with Eli Manning, Tim Hasselbeck, and Jared Lorenzen.

He was named the third-string quarterback in a season that saw the team win Super Bowl XLII, beating the previously undefeated New England Patriots.