In 2008, Antidote completed several documentaries, including Soul Power and The Dungeon Masters, both of which premiered at the 2008 Toronto International Film Festival.

Antidote produced Roman Polanski: Wanted and Desired, a documentary directed by Marina Zenovich, which was nominated for the Grand Jury Prize and winner of the Documentary Editing Award at the 2008 Sundance Film Festival, the film will be released domestically by HBO and internationally through The Weinstein Company.

In 2003, Daily Variety announced Antidote's plans for a film adaptation of the JT LeRoy novel 'Sarah', to be directed by Steven Shainberg.

"[7] In June 2007 Antidote sued Albert for fraud, claiming that a contract signed with JT LeRoy to make a feature film of Sarah was null and void.

"[7] After an appeal, the damages awarded were reduced by settlement with Antidote in 2009, and Laura Albert retained the rights to her books and her life story.