Antigua and Barbuda competed in the 2010 Commonwealth Games held in Delhi, India, from 3 to 14 October 2010.

[1] Despite concerns about safety and their accommodations, the team planned to compete.

[1] Antigua and Barbuda competed in athletics, cycling, shooting, swimming and boxing.

[1] The delegation was made up of seventeen athletes and nine officials.

[2] Antigua entered one boxer into the light heavyweight classification.