Antigua and Barbuda participated in the 2011 Commonwealth Youth Games in Isle of Man from 7 to 13 September 2011.

The delegation of Antigua and Barbuda for the 2011 Commonwealth Youth Games consisted of nine people including six competitors – five men, one woman – and three officials.

Five athletes — Tahir Walsh, Jared Jarvis, Cejaeh Greene, Mark Phillips and Viani Joseph — were selected for athletics events, and one, William "Trey" Smith, represented the nation in swimming.

[1] Tahir Walsh, Jared Jarvis, Cejaeh Greene and Mark Phillips constituted the 4×100 meters relay team.

The sole female athlete to represent the nation, Viani Joseph, competed in the 200 and 400 meters sprints.