Upon the death of the king in 1713, Pesne worked in the courts of Dresden and Dessau, and later visited London and Paris, where he was made a full member of the Académie Royale in 1720.
In St. Agnus Church in Köthen, where J. S. Bach was music director (Kapellmeister), there is a portrait of the donor Gisela Agnes, Princess of Anhalt-Köthen, painted by Pesne in 1713.
In 1746 Pesne received from King Frederick II property and construction material to erect a house at Oberwallstraße 3 in Berlin, where he lived until his death in 1757.
Pesne used a style similar to that made famous in France during the reign of Louis XIV, although his use of colors was softer and his touch more "painterly."
[3] Most of his decorative work at Rheinsberg and later in Berlin and Potsdam at Sanssoucci, included mythological and allegorical scenes, such as the ceiling in the audience room at Sanssouci: Zephyr Crowns Flora.