During his career, Sistermans premiered important compositions by Johannes Brahms and Gustav Mahler, and also had lieder dedicated to him by Hans Pfitzner, Eugen d'Albert and Alexander von Zemlinsky.
In his later years, Sistermans served as a teacher at the Royal Conservatory of The Hague and conductor of a church choir in Rotterdam.
[6][7] On 9 November of the same year,[8] Sistermans gave the first performance of Johannes Brahms's Vier ernste Gesänge in Vienna with pianist Coenraad V.
[3][9] The composer declined Sisterman's requests to be the pianist at the premiere performance, likely because Brahms could not bear to hear the songs in light of the imminent death of Clara Schumann, with whom they were closely associated.
Edvard Grieg requested Sistermans, who was then "by some considered the best singer of Lieder", to sing his Scenes from Olav Trygvason at the Leeds Festival on 16 October 1907.