Antonella Serra Zanetti (born 25 July 1980; Italian pronunciation: [antoˈnɛlla ˈsɛrra ddzaˈnetti]) is a former professional tennis player from Italy.

On 30 January 2006, Serra Zanetti achieved her career-high singles ranking of world No.

Antonella was coached by Patricio Remondegui, her favorite surface is hardcourt.

Father Alessandro is in banking; mother Arianna is an art history teacher; older brother Andrea and younger sister Alessia are students.

Older sister Adriana also retired as professional tennis player.