Highly educated and generous, she was the sister of Duke Eberhard III of Württemberg, who more than his father played an important role in the Thirty Years War.

Her charity, piety, gift for languages and all-encompassing scholarship were widely praised, and she became celebrated as "Princess Antonia the learned", and "the Minerva of Württemberg".

[1] She became a close associate of the evangelical Protestant theologian and mystical symbolist Johann Valentin Andreae, and later was on friendly terms with the founder of the Pietism movement, Philip Jacob Spener.

[1] Her specifically Christian expression of this tradition found its culmination in the unique large Kabbalistic triptych painting designed and commissioned by Princess Antonia and her academic teachers in 1652, installed in 1673 in the small town church of Holy Trinity at Bad Teinach-Zavelstein in the Black Forest, a personal witness of faith.

[1] An increased interest in the Hebrew language among Christian scholars was one of the effects of the Reformation in Germany, and royal and noble families included it sometimes even in the curriculum of their daughters' education.

There is a manuscript extant in the Royal Library of Stuttgart, entitled Unterschiedlicher Riss zu Sephiroth which is supposed to have been written by Antonia.

Her praise was sung by many a Christian Hebraist; one poem in twenty-four stanzas with her acrostic, in honour of the "celebrated Princess Antonia", has been preserved in Johannes Buxtorf's collection of manuscripts.

[4] The central panel finds a woman holding in her right hand a flaming heart (charity), with in her left an anchor (faith) and a cross (hope), standing at the threshold of a garden enclosed by a hedge of roses.