Antonio José de Irisarri Alonso (Latin American Spanish: [anˈtonjo xoˈse ðejɾiˈsari]; February 7, 1786 – June 10, 1868) was a Guatemalan statesman, journalist, and politician who served as Interim Supreme Director of Chile in 1814.

In 1809 he visited Chile, and having married Mercedes Trucíos y Larraín, an heiress there, took up his residence in that country and joined with enthusiasm the movement for independence in 1810.

He was sent to Central America in 1827 as minister for Chile, and in 1837 as plenipotentiary to Peru and private adviser to Admiral Manuel Blanco during the War of the Confederation.

The governments of Guatemala and Salvador appointed him, in 1855, their minister to Washington, and for a long time he was dean of the diplomatic corps.

Irisarri continued his literary work in the United States, and was generally esteemed for his knowledge, genial character, and polished manners.