The locality is named after an early Colombian leader, Antonio Nariño, who is often referred to as the precursor to the presidency.

There is one major commercial sector in the Restrepo neighborhood, with the balance of the locality consisting of residential areas with small stores and churches.

The mass transport system of Bogotá, TransMilenio, runs on Avenida Caracas (Restrepo and Fucha stations) and Autopista Sur.

A large number of small companies are located here, with the production of low-cost, high-quality shoes among the most notable of industries.

Main neighborhoods are Restrepo, Policarpa Salavarrieta, Luna Park, Villa Mayor, Eduardo Freí, San Antonio, Caracas, Ciudad Berna, Ciudad Jardín, La Fragua, Eduardo Santos, and Santander.