Antonio Pietrangeli (19 January 1919 – 12 July 1968) was an Italian film director and screenwriter.

Pietrangeli's own directing debut was Empty Eyes, a 1953 film starring Gabriele Ferzetti.

This was followed by the Alberto Sordi comedies The Bachelor (1956) and Souvenirs d'Italie (1957).

The director's career highlights include Adua and Her Friends (1960), a drama with Marcello Mastroianni and Simone Signoret, the supernatural comedy Ghosts of Rome (1961), again with Mastroianni, The Magnificent Cuckold (1964), a comedy of adultery starring Claudia Cardinale and Ugo Tognazzi, and the comedy-drama I Knew Her Well (1965) with Stefania Sandrelli.

Pietrangeli died from drowning by accident in the Gulf of Gaeta in 1968, while working on the film How, When and with Whom.