[1][2] Antonio Ruíz de Morales y Molina was born in Córdoba, Spain and ordained a priest in the Order of Santiago.
[2] On 15 May 1566, he was appointed during the papacy of Pope Pius V as Bishop of Michoacán.
[2] On 10 December 1572, he was appointed during the papacy of Pope Gregory XIII as Bishop of Tlaxcala and installed on 8 October 1573.
[2] He served as Bishop of Tlaxcala until his death on 17 July 1576.
[2] While bishop, he was the principal consecrator of Pedro de Moya y Contreras, Archbishop of México (1573); and the principal co-consecrator of Juan de Medina Rincón y de la Vega, Bishop of Michoacán (1574).