Anuradha was born in Chennai to playback singer Renuka Devi and Meenakshi Sundaram Mohan.
She was given a fellowship to do her Master of Arts degree in Ethnomusicology and Composition from Wesleyan University, Connecticut, United States.
She also collaborates with her husband Sriram Parasuram on their classical music Jugalbandhi concerts[5] and their TV programme Elaame Sangeetham Thaan.
Having sung more than 2,000 songs in Tamil, Telugu, Kannada, and Malayalam, and six North Indian languages, some of her hits are "Nalam Nalam Ariyaaval" (Kaadal Kotai), "Dilruba Dilruba" (Priyam), "Meenamma" (Aasai), "Acham Acham Illai" (Indira), "Phenk Hawa" (Ram Jaane) and "Pehli Pehli" (Zor).
She has composed music for the film Five Star and television series Sivamayam produced by Radaan for Sun TV along with her husband.