[4] Exposure to this species with dogs has been associated with the development of neurotoxicosis, with symptoms ranging from respiratory distress to tremors, muscle fasciculations, and seizures.

[4] Aplysia gigantea are commonly found near the southwestern corner of Western Australia, in soft sediment or reef environments.

[1] Due to the phenotypic similarity with Aplysia extaordinaria, it has been suggested by marine biologist Bill Rudman that these may be the same species.

Additionally, they are distinguished by large paradopia on their backs, which function as limbs allowing the sea hare to swim for short periods of time.

[6] When ingested by domestic dogs, several symptoms have been recorded, including respiratory issues, ptyalism, emesis, ataxia, and hyperaesthesia.

[2] The eggs produced by A. gigantea are in long and stringy clumps, and hatch into planktonic larvae which feed on microscopic algae.