The Roman Catholic Diocese of Mbujimayi (Latin: Mbugimayen(sis)) is a Latin diocese in the Democratic Republic of the Congo's Kasai Oriental province.
It is a suffragan in the ecclesiastical province of Kananga.
Its cathedral episcopal see is the Cathédrale Saint-Jean-Baptiste de Bonzola in the city of Mbuji-Mayi.
(all Latin Rite)