The Roman Catholic Archdiocese of Mbandaka-Bikoro (Latin: Mbandakan(us)–Bikoroën(sis)) is the Metropolitan See for the Latin Rite Ecclesiastical province of Mbandaka-Bikoro, in the western part of Democratic Republic of the Congo.
It is under the authority of the Congregation for the Evangelization of Peoples.
The cathedral archiepiscopal see is at the Cathedral of St. Eugene, in Mbandaka, Équateur Province.
As per 2015, it pastorally served 646,000 Catholics (52.4% of 1,232,000 total population) on 95,000 km² in 34 parishes with 87 priests (56 diocesan, 31 religious), 238 lay religious (82 brothers, 156 sisters) and 42 seminarians.
Its suffragan sees are :