The Vicariate Apostolic of Ñuflo de Chávez (Latin: Apostolicus Vicariatus Niuflensis) is a Latin Church missionary ecclesiastical territory or apostolic vicariate of the Catholic Church in Bolivia.

It is immediately exempt to the Holy See.

Its cathedra is located in the episcopal see of Concepción, Santa Cruz.

On 13 December 1951 Pope Pius XII established the Vicariate Apostolic of Ñuflo de Chávez from the Vicariate Apostolic of Chiquitos.

This article on a Roman Catholic diocese in Bolivia is a stub.