The Apostolic Vicariate of Anatolia (Latin: Vicariatus Apostolicus Anatoliensis, Turkish: Anadolu Havarisel Vekilliği) is a Roman Catholic Latin apostolic vicariate in the eastern half of Anatolia (Asian Turkey).

The missionary pre-diocesan jurisdiction is not part of any ecclesiastical province.

It is under the direction of the Congregation for the Oriental Churches, an unusual structure for a Latin see, and directly dependent on the Holy See.

As of 2020, the vicariate, which covers 450k square kilometers, had six parishes and two missions to serve a thousand Turkish Christians as well as Christian refugees from Syria, Iraq, Iran, Afghanistan, and Pakistan.

This article on a Roman Catholic diocese in Asia is a stub.