The Apostolic Vicariate of Southern Arabia (Latin: Vicariatus Apostolicus Arabiæ Meridionalis; Arabic: النيابة الرسولية من جنوب الجزيرة العربية) is an apostolic vicariate of the Catholic Church with territorial jurisdiction over Oman, United Arab Emirates and Yemen.

On 25 April 1888, Pope Leo XIII made the Apostolic Vicariate of Aden, located in Yemen.

On the 28 June 1889, the name was changed to the Vicariate Apostolic of Arabia, responsible for the countries of the Arabian Peninsula and surrounding region: Bahrain, Oman, Saudi Arabia, Qatar, United Arab Emirates, Somalia and Yemen.

In 1973, the see of the jurisdiction was transferred from Aden to St. Joseph's Cathedral in Abu Dhabi.

[9] A subsequent redrawing of boundaries in 2011 reduced its jurisdiction to the countries of Oman, the United Arab Emirates and Yemen.