Studies have shown that the lifecycles of both the host and the symbiont are affected in some way, usually negative, and that for obligate symbiosis the effects can be drastic.
A classical example of a symbiotic relationship with an aposymbiotic state is the Hawaiian bobtail squid Euprymna scolopes and the bioluminescent bacterium Aliivibrio fischeri.
Juveniles are colonized within hours of hatching and Aliivibrio must outcompete other bacteria in the seawater through a system of recognition and infection.
Aposymbiotic Euprymna juveniles have been studied throughout colonization in order to determine the system of recognizing Vibrio fischeri in seawater.
[5] This relationship between Asobara tabida wasps and Wolbachia is an important model for insect microbiome study.