His second opponent as a professional boxer, Gregorio Padrino, died two days after their bout as a consequence of the blows received in it.

[1] Guzman continued on and captured the WBA flyweight title in 1992 with an upset decision win over Yong-Kang Kim.

He lost the belt in his first defense to David Grimán by decision (scoring of judges) in 1994.

He later challenged Saen Sor Ploenchit, Alimi Goitia, and Yokthai Sithoar for their respective belts but lost each fight.

He is one of only 2 world champions in history to retire with an even record, the other being Juan Polo Perez.