Notable members of the Religious Society of Friends who worshiped at this meetinghouse include abolitionists and woman rights advocates, Sarah and Angelina Grimke.

The West Room, still used for large Quaker gatherings and private events, features interpretive panels about Friends’ worship.

The Reception Room in the center of the building has display cases which change seasonally as well as a small collection of religious books on open shelves.

The building’s basement has restrooms, and its second floor houses administrative offices and private meeting rooms not open to the public.

For most of the 19th and 20th centuries, Friends would come from Philadelphia Yearly Meeting’s four-state geographic area to conduct annual business at its midsummer “sessions”.

As of 2024, work is underway to increase the electrical service to the building to permit conversion of its gas boiler to an efficient heating and cooling system.

In the East Room, the exhibits will be refreshed to offer a more contemporary and inclusive interpretation of the Quaker experience and the testimonies of Friends.