The Archdiocese of Santiago de Cuba (Latin: Archidioecesis Sancti Iacobi in Cuba) (erected 1518 as the Diocese of Baracoa) is a Latin Church ecclesiastical jurisdiction or archdiocese of the Catholic Church in Cuba.

It is a metropolitan see with four suffragan dioceses in its ecclesiastical province: Guantánamo-Baracoa, Holguín and Santísimo Salvador de Bayamo y Manzanillo.

[1][2] Prior to elevation as a archdiocese, the Diocese of Santiago de Cuba was a suffragan of the Archdiocese of Seville in Spain until 12 February 1546 when it became a suffragan of the Diocese of Santo Domingo (now Archdiocese of Santo Domingo) in the Dominican Republic.

The archdiocese is the home of the Basílica Santuario Nacional de Nuestra Señora de la Caridad del Cobre.

Erected: 1518 Name Changed: 28 April 1522 Latin Name: Sancti Iacobi in Cuba Elevated: 24 November 1803 The see also gained territory in 1527 with the suppression of the Diocese of Concepción de la Vega.