Archduchess Maria Luisa of Austria (30 August 1798 – 15 June 1857) was an Archduchess of Austria and Princess of Bohemia, as the daughter of Ferdinand III, Grand Duke of Tuscany and Luisa of Naples and Sicily.

Archduchess Maria Luisa Giuseppa Cristina Rosa was born on 30 August 1798, in Florence.

She was the second child and first daughter borne to Ferdinand III, Grand Duke of Tuscany and his wife Luisa of Naples and Sicily.

Since her birth, Maria Luisa was disabled and had a deformity, probably linked to the genetic inbreeding within her family;[speculation?]

[citation needed] Maria Luisa and her family were known to have made regular visitations to Pisa, since 1814.