The Ardmore Historic Commercial District, in Ardmore, Oklahoma, is a 19 acres (7.7 ha) historic district which was listed on the National Register of Historic Places in 1983.

[1] The district includes 97 "major structures", in total having 133 contributing buildings.

It runs along Main St. from the former Santa Fe railroad tracks to B St., N. Washington from Main to 2nd Ave., NE., and Caddo from Main to the northern side of 2nd Ave., NE.

[2] It includes: Ardmore has an Ardmore Main Street Authority, one of the various Main Street programs which act in the interests of commercial district revitalization.

This article about a property in Oklahoma on the National Register of Historic Places is a stub.