It has been the home ground of Campeonato Brasileiro Série B club Cuiabá Esporte Clube since 2015.

Completed on 26 April 2014, it is used mostly for football and hosted four group stage matches during the 2014 FIFA World Cup.

It suffered a fire in October 2013, due to polystyrene insulation panels catching alight.

Although nobody was injured, the fire came within 24 hours of the state governor of Mato Grosso warning that it may not be finished for the World Cup.

Arena Pantanal was one of the five venues to host matches of the 2021 Copa América.