In 1937, she was placed under contract to Metro-Goldwyn-Mayer and began dubbing the voices of Jeanette MacDonald and Norma Shearer into Italian.

She became a narrator for the Voice of America, interviewing American movie stars for broadcast in Italy.

At the same time, she made her movie debut in the classic It's a Wonderful Life (1946) as Mrs. Maria Martini.

[5] Brunetti wrote and performed in daily radio shows; she became a member of the Hollywood Foreign Press Association, writing numerous articles on Hollywood personalities; she authored books, wrote music, and appeared in nearly 60 television programmes and almost 70 films.

She continued to act into her nineties, most notably as a relative from the Old World who visits and stays with the (wrong) Barone family in a 1998 episode of Everybody Loves Raymond; her last role was in 2002.