Argyle is a town in Osage and Maries counties in the U.S. state of Missouri.

Argyle is on the north side of Loose Creek, approximately 1.5 miles (2.4 km) west of the Maries River.

It is on Missouri Route T, and Koeltztown lies about 2 miles (3 km) to the north.

According to the U.S. Census Bureau, the village has a total area of 0.40 square miles (1.04 km2), all land,[2] except for Loose Creek.

38.7% of all households were made up of individuals, and 18.6% had someone living alone who was 65 years of age or older.

27.7% of all households were made up of individuals, and 15.4% had someone living alone who was 65 years of age or older.

About 12.2% of families and 15.7% of the population were below the poverty line, including none of those under the age of eighteen and 17.6% of those 65 or over.