The project broke ground on 13 August 2008, with a work team of Vincentians and Cubans (nicknamed the "Chatoyer-Che Contingent" by Vincentian Prime Minister Ralph Gonsalves),[2] and the airport officially opened on 14 February 2017 when a Dynamic Airways charter flight became the first international aircraft to touch down at Argyle.

The airport is expected to increase the accessibility to this multi-island destination and be a key economic driver for the country, attracting direct flights from Canada, the US, the UK and more, fueling investments.

The airport is a primary hub for SVG Air, a national airline of St. Vincent and the Grenadines, along with Mustique Airways.

Air Canada Rouge, American Airlines, Caribbean Airlines, Virgin Atlantic, InterCaribbean Airways, LIAT, SVG Air, Mustique Airways and One Caribbean currently provide regularly scheduled passenger services at Argyle International Airport.

Amerijet International, increased their airlift capacity, using larger aircraft, such as the Boeing 767-300, to move more cargo into and out of St. Vincent and the Grenadines.

One Caribbean has filed an application for a Foreign Air Carrier Permit with the US Department of Transportation (USDOT) ahead of plans to offer ad hoc charter flights to any point(s) in the United States from St. Vincent & the Grenadines and other OECS (Organisation of Eastern Caribbean States) countries.

If it does, they ask, can the country afford to build – and maintain – an international airport while running an EC$151 million deficit as of February 2016.

[31] In a "historic" address on 8 August 2005, Prime Minister Gonsalves stated, "Foreign investors often shy away from St. Vincent and the Grenadines when the limitations of air access arise due to the absence of an international airport."

Critics have responded saying that the prime minister's statement is invalid and incorrect: on the contrary, many foreign concerns have invested in St. Vincent and the Grenadines from as early as the 1960s, after the Arnos Vale airport was constructed (and later renamed in memory of E.T.