Argyrolagus is an extinct genus of South American metatherian, belonging to the order Polydolopimorpha from the Early Pliocene Monte Hermoso Formation, Patagonia, Argentina.

[1] Jumping on its hind legs, the 15–20-centimetre (5.9–7.9 in) long (without tail)[2] Argyrolagus resembled a gerbil or kultarr.

It had a long tail for balance, and a narrow head with a pointed snout.

Judging from its huge eyes, Argyrolagus was nocturnal.

The form of its teeth suggest that it would have fed on desert plants.