During the first half of the eighth century BC, King Argishti I of Urartu built a fortress in the area and named it Argishtikhinili.

Slabs of clay have been found from the Achaemenid period written in the Elamite language concerning episodes of the Gilgamesh epic.

Various inscriptions in Hellenistic Greek carved around the third century BC, have been found, including poetry from Hesiod, lines from Euripides, a list of Macedonian months, and names of Orontid Kings.

149 BC), he built a temple there and asked prince aspet (knight) Smbat of the Bagratuni dynasty to give up his religion and worship idols.

Movses also relates that when King Tigranes II (whom he places on the throne from 90 to 36 BC), in order to take revenge on Queen Cleopatra of Egypt, sent an expedition to Palestine, he carried a great number of Jews into captivity, and settled them in Armavir and in Vardges.

The settlement remained abandoned until 1613, when seven Armenian families rebuilt a new village just 1 km east of the ancient site of Armavir.

The Russo-Persian War (1826–1828) began due to Persian demand to reconquer the territories lost to Russia between 1804 and 1813.

When the TDFR was dissolved in May 1918, this region passed to the Democratic Republic of Armenia, having a conspicuous role in Armenian history due to Battle of Sardarapat.

There, the Armenian forces staved off extermination and repulsed the Ottoman Army whose campaign in the Caucasus was aimed at occupying Yerevan.

The Ottoman Army retreated after signing the Armistice of Mudros at the end of 1918 and so Armavir-Ghurdughuli returned to the Democratic Republic of Armenia in November 1918.