Besides its Off-off Broadway home in Hell's Kitchen, Ars Nova also operates the former Barrow Street Theatre at Greenwich House as a space for Off-Broadway productions.

Past acts have included Clydesdale Erotic, Justin Levine, Langhorne Slim, Semi Precious Weapons, Jay Brannan, The Woes, The Defibulators, Cynthia Hopkins, and The Spring Standards.

[14] ANT Fest has since become an annual event, lasting for 30 nights and giving early-career artists a forum to present original material in front of a New York audience.

[20] In 2012, the Manhattan Theatre Club launched The Studio at Stage II, with the intention of producing new works at the New York City Center.

If accepted into the two-year program, the writers are given a chance to develop their plays with peer support and input, culminating in a public reading of their completed works.

Ars Nova's 2012 Artists in Residence are The Debate Society (Company-in-Residence), Portia Krieger (Director-in-Residence) and Shaina Taub (Composer-in-Residence).

Each resident has access to the Ars Nova staff and resources, in return for providing expertise and assistance with artistic planning and production.