GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease.

[7] Artemin promotes the survival of newly differentiated neurons after they have undergone terminal mitosis.

[8] Artemin plays an important role in migration, proliferation, and differentiation of sympathetic neurons during development.

However, during target innervation, sympathetic neurons become dependent on neural growth factor for survival support.

[10] This article incorporates text from the United States National Library of Medicine, which is in the public domain.