In January 1892, Busch emigrated to the United States, and was employed as a draftsman at William Cramp & Sons Shipbuilders in Philadelphia.
The entire project was completed in twelve months, and Busch was honored with the Order of the Rising Sun, 4th class by Emperor Meiji.
In 1909, Busch established the American Architectural Shipbuilding and Development Company, and proposed designed for miniature submarines to the Japanese government.
During his long career, Busch was responsible for the design and development of many ship classes for the United States Navy and contributed to their production at some of the country's largest shipyards through both World Wars.
After World War I, Busch changed his last name to Du Busc in 1919 - this was most probably due to the large amount of anti-German sentiment that existed in the United States during that time though his family lineage was of Huguenot origins.