It is the referral hospital for the districts of Adjumani, Arua, Koboko, Maracha, Moyo, Nebbi, Yumbe, and Zombo.

The hospital also receives referrals from neighboring parts of South Sudan and the Democratic Republic of the Congo.

It is located approximately 251 kilometres (156 mi), by road, northwest of Gulu Regional Referral Hospital.

[2] This location is approximately 496 kilometres (308 mi), by road, northwest of Mulago National Referral Hospital, in Kampala, Uganda's capital and largest city.

[5] The hospital is designated as one of the fifteen (15) Internship Hospitals in Uganda where graduates of Ugandan medical schools can serve one year of internship under the supervision of qualified specialists and consultants.