The Ashanti Region is located in the southern part of Ghana and is the third largest of 16 administrative regions, occupying a total land surface of 24,389 km2 (9,417 sq mi) and making up 10.2 percent of the total land area of Ghana.

[6] The center of population in the Ashanti Region is located in the Kumasi Metropolitan District.

The majority of the Ashanti Region's population is from the Akan ethnic group and is made up of citizens by birth (94.2%), whereas 5% are naturalized Ghanaians.

Akans are the predominant ethnic group in the region, representing 94.2% of citizens by birth.

[5] The Ashanti region is served by the Kumasi Airport, which handles domestic flights.

Under its administrative system, the region is divided into 43 MMDAs (made up of 1 Metropolitan, 18 Municipal and 24 Ordinary Assemblies).