[2] Keddie won the 2013 Gold Logie award for Most Popular Personality on Australian Television, for her role as Dr Nina Proudman in the Network Ten drama Offspring.

[3] As a child, she took dancing lessons for nine years and at age 14, she dislocated her knee prior to an audition at the Australian Ballet School.

In 2000 she scored a starring role as dancer in the music video, “Since I Left You” by the Avalanches, which by 2024 had been viewed 16 million times.

This role led to Keddie being nominated for various awards for playing the part of Julia Jackson, a woman who struggles to cope with her own identity in the midst of family tragedy.

She portrayed police officer Liz Cruickshank in the television drama Underbelly: A Tale of Two Cities and journalist Jacinta Burns, in the TV series Rush, as well as Dr Carol Frost in X-Men Origins: Wolverine.

Ballard faces an election campaign alongside newly announced Opposition candidate David McLeod (Rodger Corser), with whom she once had a tumultuous affair.

In 2021, Keddie played Heather Marconi in the Nicole Kidman led Hulu series, Nine Perfect Strangers alongside Melissa McCarthy, Samara Weaving and Bobby Cannavale.

Her performances in the 2005 Melbourne Theatre Company production of Les Liaisons dangereuses, and the Playbox's The Ishmael Club, both earned her Green Room Award nominations.

[12] In 2007 Keddie starred alongside Jay Bowen in the Melbourne Theatre Company's play The Glass Soldier written by Hannie Rayson.