[2] Perlow was born in 1759 to Rabbi Aharon of the Great of the Karlin dynasty and his wife Leah.
Following Shlomo's passing in 1792, most of his disciples turned to Perlow for guidance, serving in Karlin.
Following a prohibition of Hasidim from growing payos in the locality, he moved his residence to Stolin.
[5] He encouraged his followers to immigrate to Eretz Yisrael, and worked to raise funds for the emigration.
[8][9] Aharon bore a son, Rabbi Shlomo Chaim Perlow, who founded the Koidanov dynasty after studying under Asher.