[1] Yoshihisa was the son of the eighth shōgun Ashikaga Yoshimasa with his wife Hino Tomiko.

[2] Since the almost 30-year-old shōgun Yoshimasa had no heir by 1464, he adopted his younger brother Ashikaga Yoshimi to succeed him.

[1] After the Ōnin war, Rokkaku Takayori, daimyō of southern Ōmi Province, seized land and manors owned by nobles of the imperial court, temples, and shrines.

In 1487, Yoshihisa led a campaign (Rokkaku Tobatsu) against Takayori but died unexpectedly, leaving no heir.

[citation needed] The years in which Yoshihisa was shōgun are more specifically identified by more than one era name or nengō.