Asimov's Biographical Encyclopedia of Science and Technology is a history of science by Isaac Asimov, written as the biographies of initially 1000 scientists and later with over 1500 entries.

For example, the article about John Franklin Enders [1195] has the sentence "Alexander Fleming's [1077] penicillin was available thanks to the work of Howard Florey [1213] and Ernst Boris Chain [1306] .

This allows one to quickly refer to the articles about Fleming, Florey, and Chain.

The alphabetical list of biographical entries starts with ABBE, Cleveland [738] and ends with ZWORYKIN, Vladimir Kosma [1134] In the Second Revised Edition Isaac Newton receives the greatest coverage, a biography of seven pages.

Dutch writer Gerrit Krol said about the book, "One of the charms of this encyclopedia is that to each name he adds those with whom this scientist has been in contact."