The Asmat–Muli Strait languages are a branch of the Trans–New Guinea languages spoken along the southern coast of Indonesian New Guinea, established by Timothy Usher and Edgar Suter.

[1] Protoforms of basic vocabulary include *moi 'water', *iafVnV 'ear', *uase 'name', *awoɣ 'breast'.

[1] Asmat–Muli Strait consists of two primary subgroups:[2] Proto-Asmat–Muli Strait is reconstructed with 12 consonants and 5 vowels:[1] Vowels are *a *e *i *o *u.

Some lexical reconstructions by Usher (2020) are:[1]