[6] In 1949, the FMDM Sisters were invited by the local government for a nursing post in the Tuberculosis section of Tan Tock Seng Hospital in Singapore.

[7][6] The Sisters campaigned for funds to build a Catholic hospital in the country after Singapore recovered from the Japanese Occupation.

Assisi Home began to admit only cancer patients requiring respite and hospice care.

[6] As a center for palliative care, Assisi Hospice also admitted patients with non-cancer diagnoses, as it recognized the significant suffering among those with other life limiting illnesses.

[2] As of 2012, Assisi Hospice had a capacity of 37 beds and 90 staff, of which five were full-time doctors trained in palliative care.

[9] The current building occupied by Assisi Hospice used to be a convent belonging to the Franciscan Missionaries of the Divine Motherhood nuns.