The village lies at the foot of the Chiltern Hills, between the Wendover and Aylesbury arms of the Grand Union Canal.

Surrounding towns include Wendover to the south, Aylesbury to the west, and Tring to the east - across the nearby county border with Hertfordshire.

The manor, later to be known as Aston Clinton, was for a short period after 1100 under the control of Edward de Salisbury, who was King Henry I's standard-bearer.

On 22 September 1934, a twin-engined biplane named Youth of New Zealand of Sir Alan Cobham's National Aviation Displays, crashed into a field near the canal at Aston Clinton.

The BAFTA and Oscar winning special effects make-up artist David Malinowski lives in the village.

[10][11][12] Australian Formula One driver Mark Webber lists Aston Clinton as his home in England where he lives with his partner Ann Neal.

[13] Robert Hendry Morton (25 September 1927 – 6 May 2002) was an English professional footballer, born in Aston Clinton, and who played for Luton Town.

[19] Between 2016 and 2021, further developments added 93 houses at Aston Brook (fields adjacent to Brook Street & College Road South, built by Bovis Homes) and 143 houses at Estone Grange (fields leading from Chapel Drive, built by Bellway).

[21] The village lies on several bus routes, with direct services to Aylesbury, Tring, Berkhamsted, Hemel Hempstead, Cheddington, Dunstable and Watford.