During the Axis occupation of Greece (1941–44), Athens was controlled by German military forces, and the line was used for the transport of troops and weapons.

On 1 January 1971, the station and most of the Greek rail infrastructure were transferred to the Hellenic Railways Organisation S.A., a state-owned corporation.

Freight traffic declined sharply when the state-imposed monopoly of OSE for the transport of agricultural products and fertilisers ended in the early 1990s.

The final service departed the unmodernized Larissis Station on 4 June 2017 before it was closed for various upgrades, including the installation of a railway electrification system.

[12] The Athens Metro station, inaugurated on 28 January 2000, lies underground and is served by Line 2 between Anthoupoli and Elliniko.

[14] In the meantime, trains will continue to use the platforms and tracks built during the previous upgrade, located where the goods yard of the old Peloponnese Station once stood.

[22] The underground Larissa Station is served by Athens Metro Line 2 trains towards Anthoupoli to the north, and Elliniko to the south.