The men's 4 × 100 metres relay event at the 1960 Olympic Games took place between September 7 and September 8.

[1] The fastest three teams in each of the four heats advanced to the semifinal round.

Heat one Heat two The United States team (of Frank Budd-Ray Norton-Stone Johnson-Dave Sime) finished first in a world record time of 39.4 s but were disqualified because at the first exchange from Budd to Norton, Norton started too early and the exchange happened outside the changeover box.

The West German team who finished second in 39.5 s received the gold medals and became the new world record holders.

Key: WR = world record; =WR = equalled world record; DQ = disqualified; * = competed in heats only