These are the official results of the 4 × 100 metres relay event at the 1988 Summer Olympics in Seoul, South Korea.

There were a total number of 29 nations competing.

[1] U.S. team who was defending the gold medal won in Los Angeles was favored to win the event, but fumbled an exchange in a heat and was disqualified.

A French team, including three members of the bronze medal-winning team here, would claim the world record two years later.

These were the standing World and Olympic records (in seconds) prior to the 1988 Summer Olympics.